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  • Multiple Myeloma & MRD
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    What is Multiple Myeloma?
    MM is a blood cancer characterized by the clonal expansion of plasma cells in the bone marrow. Myeloma is rare, accounting for 1% of all cancers.
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    MM diagnosis and monitoring
    Multiple myeloma diagnosis and monitoring are based on clinical symptoms and a variety of laboratory tests. M-protein detection and quantification are integral parts of diagnosis and monitoring of MM.
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    What is MRD ?
    MRD stands for Minimal Residual Disease. It refers to the very small number of myeloma cells that are present in the bone marrow after treatment. These remaining cells often cannot be detected through traditional tests of treatment response. However, they have the potential to multiply and cause relapse.
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  • What is Multiple Myeloma?
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Author: cbernier@sebia.com

August 2023

CAP/CLIA Accreditation for Laboratory Services

June 2023

MRD Monitoring by Targeted Mass Spectrometry Allows Early Relapse Detection in MM – Blood 2022

June 2023

An ultra-sensitive method for sequencing and monitoring M-protein in peripheral blood – EMN 2023

June 2023

Clonotypic Features of Rearranged Immunoglobulin Genes Yield Personalized Biomarkers for MRD Monitoring in MM – Clin Chem. 2021

June 2023

Mass Spectrometry for Identification, Monitoring, and MRD Detection of M-Proteins – Clin Chem. 2020

June 2023

Multiple Myeloma MRD Detection: Targeted Mass Spectrometry in Blood vs Next-Generation Sequencing in Bone Marrow – Clin Chem. 2021

June 2023

Dynamic monitoring of myeloma minimal residual disease with targeted mass spectrometry – Blood Cancer J. 2023

June 2023

IMWG consensus criteria for response and minimal residual disease assessment in Multiple Myeloma – Lancet Oncol. 2016

June 2023

Clinical Applications and Future Directions of Minimal Residual Disease Testing in Multiple Myeloma – Front Oncol. 2020

June 2023

Making clinical decisions based on measurable residual disease improves the outcome in Multiple Myeloma – J Hematol Oncol. 2021

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