M-protein diagnostics in multiple myeloma patients using ultra-sensitive targeted mass spectrometry and an off-the-shelf calibrator
This study introduces SILuMAB-based MS-MRD, a method using a standardized calibrator. It demonstrates high sensitivity, reproducibility, and accuracy comparable to traditional methods. Importantly, SILuMAB simplifies the process, reduces costs, and enables quality control, making MS-MRD more accessible for clinical implementation.