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  • Multiple Myeloma & MRD
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    What is Multiple Myeloma?
    MM is a blood cancer characterized by the clonal expansion of plasma cells in the bone marrow. Myeloma is rare, accounting for 1% of all cancers.
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    MM diagnosis and monitoring
    Multiple myeloma diagnosis and monitoring are based on clinical symptoms and a variety of laboratory tests. M-protein detection and quantification are integral parts of diagnosis and monitoring of MM.
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    What is MRD ?
    MRD stands for Minimal Residual Disease. It refers to the very small number of myeloma cells that are present in the bone marrow after treatment. These remaining cells often cannot be detected through traditional tests of treatment response. However, they have the potential to multiply and cause relapse.
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Author: cbernier@sebia.com

June 2023

Minimal Residual Disease in Myeloma: Application for Clinical Care and New Drug Registration – Clin Cancer Res. 2021

June 2023

Minimal Residual Disease Assessment in Multiple Myeloma Patients: Minimal Disease With Maximal Implications – Front Oncol. 2022

June 2023

Extramedullary disease in multiple myeloma: a systematic literature review – Blood Cancer J. 2022

June 2023

Modern Myeloma Therapy + Sustained Minimal Residual Disease-Negative = (Functional) Cure! – Journal of Clinical Oncology, 2022

June 2023

Mass spectrometry for the evaluation of monoclonal proteins in MM and related disorders – Blood Cancer J. 2021

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